15,364 research outputs found

    Do tasks make a difference? Accounting for heterogeneity of performance of children with reading difficulties on tasks of executive function : findings from a meta-analysis

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    Research studies have implicated executive functions in reading difficulties (RD). But while some studies have found children with RD to be impaired on tasks of executive function other studies report unimpaired performance. A meta-analysis was carried out to determine whether these discrepant findings can be accounted for by differences in the tasks of executive function that are utilized. A total of 48 studies comparing the performance on tasks of executive function of children with RD with their typically developing peers were included in the meta-analysis, yielding 180 effect sizes. An overall effect size of 0.57 (SE .03) was obtained, indicating that children with RD have impairments on tasks of executive function. However, effect sizes varied considerably suggesting that the impairment is not uniform. Moderator analysis revealed that task modality and IQ-achievement discrepancy definitions of RD influenced the magnitude of effect; however, the age and gender of participants and the nature of the RD did not have an influence. While the children's RD were associated with executive function impairments, variation in effect size is a product of the assessment task employed, underlying task demands, and definitional criteria

    Results from the ALEPH experiment at LEP 2

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    High energy data from LEP are used to make precise measurements of parameters of the standard model, and to search for physics beyond it. W pairs are studied, enabling a number of independent measurements of the W mass and studies of W decays. Limits are presented for the masses of neutral and charged Higgs particles, while searches for supersymmetric particles have allowed significant regions of SUSY parameter space to be excluded. Lower limits on the masses of neutralinos, charginos, sleptons and squarks are presented, and supergravity and RR-parity violating models are investigated

    Randomised positive control trial of NSAID and antimicrobial treatment for calf fever caused by pneumonia

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    One hundred and fifty-four preweaning calves were followed between May and October 2015. Calves were fitted with continuous monitoring temperature probes (TempVerified FeverTag), programmed so a flashing light emitting diode (LED) light was triggered following six hours of a sustained ear canal temperature of ≥39.7°C. A total of 83 calves (61.9 per cent) developed undifferentiated fever, with a presumptive diagnosis of pneumonia through exclusion of other calf diseases. Once fever was detected, calves were randomly allocated to treatment groups. Calves in group 1 (NSAID) received 2 mg/kg flunixin meglumine (Allevinix, Merial) for three consecutive days and group 2 (antimicrobial) received 6 mg/kg gamithromycin (Zactran, Merial). If fever persisted for 72 hours after the initial treatment, calves were given further treatment (group 1 received antimicrobial and group 2 received NSAID). Calves in group 1 (NSAID) were five times more likely (P=0.002) to require a second treatment (the antimicrobial) after 72 hours to resolve the fever compared with the need to give group 2 (antimicrobial) calves a second treatment (NSAID). This demonstrates the importance of ongoing monitoring and follow-up of calves with respiratory disease. However, of calves with fever in group 1 (NSAID), 25.7 per cent showed resolution following NSAID-only treatment with no detrimental effect on the development of repeated fever or daily live weight gain. This suggests that NSAID alone may be a useful first-line treatment, provided adequate attention is given to ongoing monitoring to identify those cases that require additional antimicrobial treatment

    Lateral Load Behavior and Capacity of Structures Composed of Steel-Plate Composite (SC) Walls

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    The structural behavior and design of steel-plate composite (SC) nuclear power plant structures has been an active research area in recent years. The use of SC construction in new power plants is part of a trend in the industry towards more economical construction through increased use of modularization and prefabrication. Power plant structures are constructed with numerous structural walls that make up the external shield building, internal shield walls, and additional walls within the containment internal structure. Thorough understanding of the structural behavior of these walls and systems of connected walls is important since they are typically designed as the primary lateral force resisting system of the power plant. The objective of this research is to provide insight into the structural behavior from the perspective of the overall structural system. Prior research has studied the mechanical behavior of SC structural members (beams, shear walls, bearing walls, connections, etc.) in detail. This research aims to apply the information currently known about the fundamental behavior of SC structural members to the analysis of complete SC structural systems. Since full-scale testing of complete SC structures is impractical and expensive, this study uses a benchmarked finite element modeling approach to analyze and study the behavior of whole structures

    The Effect of Simulating Different Intermediate Host Snail Species on the Link between Water Temperature and Schistosomiasis Risk

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    Introduction: A number of studies have attempted to predict the effects of climate change on schistosomiasis risk. The importance of considering different species of intermediate host snails separately has never previously been explored. Methods: An agent-based model of water temperature and Biomphalaria pfeifferi population dynamics and Schistosoma mansoni transmission was parameterised to two additional species of snail: B. glabrata and B. alexandrina. Results: Simulated B. alexandrina populations had lower minimum and maximum temperatures for survival than B. pfeifferi populations (12.5–29.5°C vs. 14.0–31.5°C). B. glabrata populations survived over a smaller range of temperatures than either B. pfeifferi or B. alexandrina (17.0°C–29.5°C). Infection risk peaked at 16.5°C, 25.0°C and 19.0°C respectively when B. pfeifferi, B. glabrata and B. alexandrina were simulated. For all species, infection risk increased sharply once a minimum temperature was reached. Conclusions: The results from all three species suggest that infection risk may increase dramatically with small increases in temperature in areas at or near the currents limits of schistosome transmission. The effect of small increases in temperature in areas where schistosomiasis is currently found will depend both on current temperatures and on the species of snail acting as intermediate host(s) in the area. In most areas where B. pfeifferi is the host, infection risk is likely to decrease. In cooler areas where B. glabrata is the host, infection risk may increase slightly. In cooler areas where B. alexandrina is the host, infection risk may more than double with only 2°C increase in temperature. Our results show that it is crucial to consider the species of intermediate host when attempting to predict the effects of climate change on schistosomiasis

    5MW Power Upgrade Studies of the ISIS TS1 Target

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    The increasing demand for neutron production at the ISIS neutron spallation source has motivated a study of an upgrade of the production target TS1. This study focuses on a 5 MW power upgrade and complete redesign of the ISIS TS1 spallation target, reflector and neutron moderators. The optimisation of the target-moderator arrangement was done in order to obtain the maximum neutron output per unit input power. In addition, at each step of this optimisation study, the heat load and thermal stresses were calculated to ensure the target can sustain the increase in the beam power
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